Hi Shelly, when was his last dose upped? Make sure your dr. ups his dose as Kolt's weight goes up. Max has been on Enfamil Nutramigen for reflux since 3 weeks :-( Max currently weighs 17.5 lbs and he takes 1.4 mL. Also, I was told the zantac helps protect his esophagus and reduce the pain on the baby from the acid. Unfortunately spit up is just part of the game now, invest in lots of bibs