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August 15th, 2006, 06:15 PM
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EricaInOhio EricaInOhio is offline
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Join Date: May 2006
Location: Ohio
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Here is a link with lots of good information on anti-phospholipid antibodies. This includes anticardiolipin and lupus anticoagulant. These are antibodies that you may be tested for if you have recurrent m/c. These antibodies can cause blood clotting disorders as well as m/c and heart disease.

http://www.thedoctorsdoctor.com/diseases/a...id_antibody.htm

The above link does not include information about the other clotting disorders such as those caused by factor V Leiden and prothrombin mutations. For these thrombophilic disorders see the link below.

http://www.ivf.com/thrombophilia.html


Another possible cause of recurrent miscarriages that I have not seen listed here yet is a genetic mutation in the gene coding for an enzyme that is important in metabolism. This enzyme is called methylenetetrahydrofolate reductase (or MTHFR for short). Mutations of this gene result in an enzyme the functions less effectively. The result can be that your body cannot convert folic acid to the form that is important for preventing neural tube defects. In addition, it indirectly causes an increased levels of a chemical called homoceistene in your blood. Homoceistene is usually converted into important amino acids, but in this case it builds up in your blood to toxic levels. This can cause heart problems as well as being toxic to the fetus.

The link below has various tests, conditions, and treatments involving recurrent miscarriage including MTHFR mutations.

http://www.rialab.com/miscarriages_prevented.php
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