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Interesting Medical Study...


Forum: Trying to Conceive after Loss

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  #1  
May 29th, 2008, 02:13 PM
Danielley08's Avatar Mega Super Mommy
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I found this study online while searching for average implantation times:

Time of implantation of the conceptus and loss of pregnancy

Wilcox AJ, Baird DD, Weinberg CR.

Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709, USA.

BACKGROUND: Implantation of the conceptus is a key step in pregnancy, but little is known about the time of implantation or the relation between the time of implantation and the outcome of pregnancy. METHODS: We collected daily urine samples for up to six months from 221 women attempting to conceive after ceasing to use contraception. Ovulation was identified on the basis of the ratio of urinary estrogen metabolites to progesterone metabolites, which changes rapidly with luteinization of the ovarian follicle. The time of implantation was defined by the appearance of chorionic gonadotropin in maternal urine. RESULTS: There were 199 conceptions, for 95 percent of which (189) we had sufficient data for analysis. Of these 189 pregnancies, 141 (75 percent) lasted at least six weeks past the last menstrual period, and the remaining 48 pregnancies (25 percent) ended in early loss. Among the pregnancies that lasted six weeks or more, the first appearance of chorionic gonadotropin occurred 6 to 12 days after ovulation; 118 women (84 percent) had implantation on day 8, 9, or 10. The risk of early pregnancy loss increased with later implantation (P<0.001). Among the 102 conceptuses that implanted by the ninth day, 13 percent ended in early loss. This proportion rose to 26 percent with implantation on day 10, to 52 percent on day 11, and to 82 percent after day 11. CONCLUSIONS: In most successful human pregnancies, the conceptus implants 8 to 10 days after ovulation. The risk of early pregnancy loss increases with later implantation.

PMID: 10362823 [PubMed - indexed for MEDLINE]

~It doesn't say if these women had normal cycles or not, so I'm not sure if it applies to everyone...but its something to think about for ladies with recurrent loss...
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  #2  
May 29th, 2008, 02:17 PM
Eleysia's Avatar Mega Super Mommy
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wow interesting study. good info tyfs.
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  #3  
May 29th, 2008, 02:17 PM
mom 2 haley & tyler's Avatar formerly mommy2haley17
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That's very interesting. Thanks for sharing.
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  #4  
May 29th, 2008, 02:22 PM
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Very cool, I think I remember reading this before when I did a TON of research on my 1st miscarriage. I thought it was pretty interesting.
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  #5  
May 29th, 2008, 02:24 PM
Pitridge's Avatar Platinum Supermommy
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That's for sharing, it's very interesting because I had implation bleeding 15 days after I O and I m/c.
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  #6  
May 29th, 2008, 02:34 PM
Danielley08's Avatar Mega Super Mommy
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I am a google-maniac...and even prior to being a mom I've always been interested in obstetrics and gynocology...I've been talking to my DH alot lately about trying to become an L&D nurse...I wouldn't want to be an actual doc...don't think I could get myself to cut people open and do c-sections and stuff...but I could assist

We have a nursing program in the Air Force I could apply for and try to get my commission...but I have a few classes left I'd have to complete to qualify for applying...
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  #7  
May 29th, 2008, 02:36 PM
Pitridge's Avatar Platinum Supermommy
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That sounds like a wonderful idea.

I found the full article if any one is interested

http://content.nejm.org/cgi/content/full/340/23/1796
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  #8  
May 29th, 2008, 02:42 PM
jennntj13's Avatar Mega Super Mommy
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I'd definitely look into that. I could see you as a nurse and I think you'd make a dang good one. I say go for it!
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  #9  
May 29th, 2008, 02:44 PM
~DaemonMykailasMum~'s Avatar 1 of Each is such a Treat
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Wow... Interesting.. Thanks for the info ladies!
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  #10  
May 29th, 2008, 02:48 PM
Danielley08's Avatar Mega Super Mommy
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awww thanks Jenn

You made me blush...
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  #11  
May 29th, 2008, 03:27 PM
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i wonder how you'd know if you had a late implantation...?
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  #12  
May 29th, 2008, 06:14 PM
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Interesting article...

Thanks Danielle!
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  #13  
May 29th, 2008, 08:52 PM
Danielley08's Avatar Mega Super Mommy
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Mistie...from counting from the day you O till the day you get your first BFP...but in this cycle they were measuring hCG every single day...even pre-O...so as soon as it showed they started the "pregnant clock"...and like I said earlier...for women with longer than normal LP I don't think this study could really apply to them...
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  #14  
May 29th, 2008, 11:00 PM
Bakin8th's Avatar Mega Super Mommy
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Very intresting!! I wonder if they had ages taken into account?
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