[.x~KAT~x.]

Methotrexate depletes folic acid (folate or folacin) Also known as vitamin B9.

This essential vitamin is absolutely necessary in the special things a body needs to help a new pregnancy grow

Methotrexate - depletes folic acid - it wipes it from your body and so the advice not to conceive is about making sure your bodies stores of vitamin B9 gave been replaced and can 'grow' a healthy subsequent pregnancy

Our recovery, from the removal of folic acid varies from woman to woman - and in some subjects deposits of methotrexate is found in the liver up to 100 days after the medicine has been given.

The outcome of a pregnancy, if it's conceived in this three month time frame is uncertain but it's unlikely you'd be asked to consider a termination. More likely, your doctors would order regular scans and monitoring and if any problem with the pregnancy, if it were to become established, or to continue, would be reviewed.

Absence of folic acid is associated with what is called Neural Tube defect - this includes things like Spina Bifida, Hare Lip and Cleft Palate - but equally there are a number of babies born, to women who conceived after methotrexate, who are just fine - that is why doctors would be unlikely to suggest anything other than monitoring.

[mom 2 haley & tyler]

I requested to have this stickied. Thanks for the great info.

[.x~KAT~x.]

Thanks! hopefully we can get some more info on methatrexate because it is all very confusing!!

[princesskate]

Did you know Methotrexate is a chemotherapy drug too? I am trying to dig up some info but what Kat said pretty much says it all