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wondering if I should ask for progesterone, opinions/experiences please?


Forum: Trying to Conceive after Loss

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  #1  
March 31st, 2010, 07:48 AM
trusting and believing
Join Date: Dec 2009
Location: Texas
Posts: 593
brief background:

2 chemicals + 1 suspected chemical
28-29 day cycles, ovulation always CD 13 or 14, occasionally CD 15
short periods--3 days + a day or two of spotting is the MOST; sometimes 2-2.5 day periods
Protein S deficiency & Heterozygous C MTHFR mutation


doc said to go on baby aspirin then Lovenox as soon as +hpt, but I believe this method has failed because like I said above I am pretty sure I have had another chemical but never could get to the point of having a positive hpt

I've always assumed that my progesterone was in check because my post-ovulatory temps are pretty good, but they do seem slow rising over the first few days after O.

What are your experiences regarding progesterone? I am thinking it may help to thicken the lining (which may be of concern since periods are shortish) or to boost the slow rise. And I have read online of women who are in the rare category where their own progesterone is just fine *until* they are pregnant and then it becomes a problem.

Should I ask for it?
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  #2  
March 31st, 2010, 08:00 AM
zkat's Avatar Mega Super Mommy
Join Date: Aug 2009
Posts: 2,623
You can always request a progesterone draw 7 dpo to see actual levels. Are you taking B6/B12 and Folic acid with the BA in the TWW? I don't start the BA until after o confirmed b/c research suggests that BA can luetenize the egg (Kary had it happen the 2 cycles prior to the BFP)

FWIW - I am Protien S deficient, Protien C borderline and Homo for A MTHfr. My periods are also very light. Used to be 1 day of light flow + 2 days of super light spotting. Since going on the folic acid/BA therapies, my periods have been 2 days light + 3 days of light spotting. My theory that has no scientific proof at all is that PSD makes your blood thicker, so it is more dense and concentrated. I am also a very slow to bleed person when cut. I never noticed it, but DH asked when we got the DX - is that why you never, ever bleed when you cut yourself?!

I have had the progesterone checked 5 dpo and it was very high - over 18 I think.

Good Luck!
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  #3  
March 31st, 2010, 08:38 AM
trusting and believing
Join Date: Dec 2009
Location: Texas
Posts: 593
Quote:
Originally Posted by zkat View Post
You can always request a progesterone draw 7 dpo to see actual levels. Are you taking B6/B12 and Folic acid with the BA in the TWW? I don't start the BA until after o confirmed b/c research suggests that BA can luetenize the egg (Kary had it happen the 2 cycles prior to the BFP)

FWIW - I am Protien S deficient, Protien C borderline and Homo for A MTHfr. My periods are also very light. Used to be 1 day of light flow + 2 days of super light spotting. Since going on the folic acid/BA therapies, my periods have been 2 days light + 3 days of light spotting. My theory that has no scientific proof at all is that PSD makes your blood thicker, so it is more dense and concentrated. I am also a very slow to bleed person when cut. I never noticed it, but DH asked when we got the DX - is that why you never, ever bleed when you cut yourself?!

I have had the progesterone checked 5 dpo and it was very high - over 18 I think.

Good Luck!
Yes, I learned from this board to start BA only after O. The month that I was doing it all cycle long, I am pretty sure I had an anovulatory cycle.

I have folic acid in my prenatal and I take an additional 400mg, so total is 1200mg. Should go for more than that?

Thank your for your theory on progesterone and blood thickening. You could be right since afterall, we are warned about blood clotting with birth control pills. Definitely something to think about though. Ob/gyn says she will put me on progesterone for certain after a bfp--hopefully the Lovenox will keep any progesterone-induced clotting from forming.
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  #4  
March 31st, 2010, 09:05 AM
Kary♥RN's Avatar Platinum Supermommy
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I did alot of investigation work on progesterone... depending on what study you read... some yes it will help you from m/c.... others say you have low progesterone because the pregnancy will fail anyway. It all depends on the study..

As for your history.. your periods sound alot like what mine are when my body is "normal".. After my losses.. sometimes it took 7 months to get back to "normal".. With that being said.. thier was alot of months that I swore I was pregnant.. and never got a + hpt... so I know I wasn't. Even with a "chemical" pregancy you will get a + hpt...
I know some ladies swear they never get a + hpt... I am not sure I buy it 100%. When you are pregnant.. you start producing HCG. HCG goes into you blood and urine. Yes I am sure.. thier is times when their dates will be off... but I would like to see medical article... not it happened to my sister's, cousins, aunt.
I know for me... After 3 confirmed losses.. My Dr said progesterone can't hurt.. can only help if that is the problem. So he was going to put me on it after ovulation on the next cycle (that would have been Sept).... But I got a BFP in Aug... only to m/c my numbers never doubled. When I went in for CD3 blood work and u/s in Nov first cycle after my m/c.. It was shown I had no mature follies that would release an egg.. I was than put on clomid... and my Dr always puts you on Progesterone while on Clomid since clomid can break down your linning. After my third cycle.. I got my BFP.. (Like Kat said.. I also stoped taking my Baby aspirin prior to ovulation)..... I have been on the progesterone since ovulation..

Here are some links.. to help you make a more informed choice..

Progesterone - Using Progesterone to Prevent Recurrent Miscarriage

Causes

The Misdiagnosed Miscarriage :: View topic - The importance of progesterone and progesterone supplements

After everything.... My Dr said it best... It can't hurt...
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  #5  
March 31st, 2010, 09:57 AM
trusting and believing
Join Date: Dec 2009
Location: Texas
Posts: 593
Quote:
Originally Posted by Kary♥RN View Post
I did alot of investigation work on progesterone... depending on what study you read... some yes it will help you from m/c.... others say you have low progesterone because the pregnancy will fail anyway. It all depends on the study..

As for your history.. your periods sound alot like what mine are when my body is "normal".. After my losses.. sometimes it took 7 months to get back to "normal".. With that being said.. thier was alot of months that I swore I was pregnant.. and never got a + hpt... so I know I wasn't. Even with a "chemical" pregancy you will get a + hpt...
I know some ladies swear they never get a + hpt... I am not sure I buy it 100%. When you are pregnant.. you start producing HCG. HCG goes into you blood and urine. Yes I am sure.. thier is times when their dates will be off... but I would like to see medical article... not it happened to my sister's, cousins, aunt.
I know for me... After 3 confirmed losses.. My Dr said progesterone can't hurt.. can only help if that is the problem. So he was going to put me on it after ovulation on the next cycle (that would have been Sept).... But I got a BFP in Aug... only to m/c my numbers never doubled. When I went in for CD3 blood work and u/s in Nov first cycle after my m/c.. It was shown I had no mature follies that would release an egg.. I was than put on clomid... and my Dr always puts you on Progesterone while on Clomid since clomid can break down your linning. After my third cycle.. I got my BFP.. (Like Kat said.. I also stoped taking my Baby aspirin prior to ovulation)..... I have been on the progesterone since ovulation..

Here are some links.. to help you make a more informed choice..

Progesterone - Using Progesterone to Prevent Recurrent Miscarriage

Causes

The Misdiagnosed Miscarriage :: View topic - The importance of progesterone and progesterone supplements

After everything.... My Dr said it best... It can't hurt...
Kary, thank you for your input. I am finally going to see an RE and my appt. I will be 3dpo, so I will see if he suggests/agrees with progesterone or not based on my history. It will be the right day to start it if he says so.

As for my last "suspected" loss, when my AF came I told myself that I had obviously imagined all of those symptoms or made them to be more than they were, but a few hours into AF I started to pass many many clots--that is typical with me and chemical pregnancies. So there really is not much anyone can say to convince me otherwise. I know my body. I don't know why I never got a positive, but I read on message boards all the time of women saying they got a positive urine test later, sometimes a week after missed AF, some say months, and I've even read an instance or two where the women said they just don't ever get positive urine tests.

Thanks again for your help-I hope you and the little twinsies are doing well.
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  #6  
March 31st, 2010, 11:51 AM
ak_mommie_of_4's Avatar Mega Super Mommy
Join Date: May 2005
Posts: 1,504
Kary-

How long to you have to be on progesterone? Is it vaginal supository or an injection? My Dr. said since my last m/c was likely due to low progesterone that once I got a bfp I would be put on the injections.
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