Wow. This is a hard question for me. I too loved the Hangover and thought it was hilarious, but I dunno if I would call it my favorite comedy.
I love comedies, especially the ridiculously stupid ones from the 70's and 80's (Naked Gun, Hot Shots, Airplane, National Lampoons, Caddyshack). They just do not make them like they used to. So I could not give you a definate answer. I am looking forward to seeing Hangover 2 though.