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Elevated Prolactin? TTC


Forum: Trying to Conceive after Loss

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  #1  
December 19th, 2012, 01:21 PM
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Join Date: Dec 2011
Posts: 49
I had a miscarriage in April, and have been TTC since, with no luck. I bleed for 2 weeks out of the month, the doctor has been doing lots of blood work and my estrogen/progesteron and other hormones are fine. But my prolactin has went up 2 points in the past couple weeks. I'm now waiting to hear back from her on what to do next, she talked a little about maybe having nodules on my pituitary and needing to check into that further. Has anybody else ever had this type of problem TTC and what effects did it have on you? Thanks!
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  #2  
December 19th, 2012, 04:42 PM
ohnicole's Avatar Platinum Supermommy
Join Date: Nov 2009
Posts: 5,756
When I was seeing a RE for fertility issues, we discovered that I had high prolactin levels. Mine turned out to be related to hypothyroidism. Were thyroid hormones tested for you? If so, you should make sure you find out your TSH number since a lot of doctors are using an old standard range. My RE likes to keep TSH under 2.5, ideally between 1 and 2. Once my TSH was under control, my prolactin was back to normal.

Otherwise (if it had been unrelated to thyroid issues) I do remember my doctor explaining that a scan (maybe a MRI?) would tell them if there was a pituitary issue and if so a medication called bromocriptine would likely resolve the high prolactin levels. I don't exactly remember the details, but I remember them being clear that it was most likely not a serious issue.

I hope that you get some answers soon
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  #3  
December 19th, 2012, 05:54 PM
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Join Date: Dec 2011
Posts: 49
oooooohhhh! I forgot to mention that I had thyroid cancer when I was 19 (8 years ago), and it was completely removed. So I take synthroid daily, and the dr keeps my tsh suppressed to keep residual tissue from growing back. They actually lowered my thryoid dose 2 weeks ago. Could this affect getting pregnant? and elevated prolactin? the 2 doctors (endocrinologist & OB/gyn) dont act like theyre really a connection? thanks
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  #4  
December 20th, 2012, 06:46 AM
ohnicole's Avatar Platinum Supermommy
Join Date: Nov 2009
Posts: 5,756
If I understood my RE correctly, when your TSH is higher, prolactin levels can increase. So maybe them lowering your synthroid dose has caused a slight increase in TSH and in prolactin levels? High prolactin levels (just like if you were breastfeeding) can cause delayed ovulation and low progesterone after ovulation, so it can impact fertility. I think if I were in your shoes I would ask for a referral to a reproductive endocrinologist, since they would have a better understanding of how your thyroid and prolactin issues will impact TTC. Good luck! And I hope it is as simple to fix as changing your synthroid dose!
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  #5  
December 23rd, 2012, 09:12 PM
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Join Date: Dec 2011
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Thanks! I go back to the doctor in a couple weeks, so hopefully they have good news!
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