I make everyones cakes from scratch except my moms. She likes box cakes haha.
If you're going to have a ton of guests I suggest just going with box cakes. You do 3 things to make the cake and you're done. With from scratch you have to put in EVERYTHING! I can get frazzled making one cake for 5 people with as much as I need to do sometimes haha.
I would say to create less stress for you, box would be the way to go. We like Duncan Heinz. That is what I buy for cupcakes or for my moms birthday

I do make my own frosting though.