Does it have to be a current TV show? If not, then my favorite show of all-time was House. If I could have had him for my doctor, I would have. I especially appreciated the rampant sarcasm. I will miss that show forever...
As for current shows, really the only other one I watch regularly is Grey's Anatomy. Although, I'm not sure how long I'll be watching it if they keep killing off the good characters...
I watch a lot of HGTV and Food Network because I have family members who watch them religiously. In generaly, though I love the true crime/forensic shows.