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Mthfr?


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  • 2 Post By plan4fate

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  #1  
December 21st, 2013, 12:24 PM
hopelessly wishing's Avatar Super Mommy
Join Date: Apr 2013
Location: California
Posts: 546
So I have an older friend who has had 2 miscarriages about the same times I had mines, but is now pg again for the third time. But this time things are going better and she has made it to 3 months.
She went for genetic testing to see why she was having the miscarriages and her dr said she had this MTHFR, something that had to do with blood clots.

I'm not 100% sure. It was a quick conversation between her and I about this.
She said I should go get checked.

DOES ANYONE KNOW ANYTHING ABOUT THIS?
She said she has to take a baby aspirin every day and I've noticed some talk about baby aspirin on here and I'm wondering if this is why?
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  #2  
December 21st, 2013, 12:38 PM
butterfly721's Avatar TTC #1
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If it is genetic, I'm not sure why she would be suggesting that you should be tested for it if you aren't related? There are a lot of reasons why people have miscarriages. But you could definitely talk to your doctor about it if you are concerned.

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  #3  
December 21st, 2013, 03:55 PM
plan4fate's Avatar I may bend, but not break
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mtfr is a clotting disorder and is VERY common. most don't know they have it because it doesn't affect daily life.

Treatment is usually baby aspirin and extra folic (I recommend skipping folic and taking actual folate in the form of metafolin). Worse cases can require injected blood thinners .

I've not been tested, but I would not be surprised to find I have it. I already do the treatment though.... 800mg folate and baby aspirin. baby aspirin has improved my af so much (I have extremely clotty af's and they're much heavier than the norm).


Clotting disorders aren't usually responsible for early miscarriages, but treatment starts for them as soon as possible because taking a chance isn't worth it.

also... doctors are not on the same page with each other about this. many believe that treatment is only needed if you carry both copies of the mutation. Others believe that the risk isn't worth it and that at the very least aspirin and extra folate are needed.

If you have this, and your doc says no need for treatment...find a new doctor. too many women who receive no treatment still have late 1st tri losses or early 2nd tri losses from blood flow issues or clots.
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Awesome siggy made by Jaidynsmum

Me: Hashi's, PCOS, Insulin resistant, Multiple miscarriages
Polypectomy - 08/21/14 Laproscopy - 12/05/2014
Him: MFI low count, low morphology, low motillity
Seeing MFI specialist/RE in 2015. Vitamins started August 2nd
Cycle 1: Clomid cd3-7 ~ bfn
Cycle 2: Clomid cd 3-7 ~ beta negative (< 3)
Cycle 3: Lap on cd 2 - Femara cd 3-7 - Testing Christmas Day
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  #4  
December 21st, 2013, 04:05 PM
hopelessly wishing's Avatar Super Mommy
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Thanks ash. That was a lot of helpful info.

She just suggested that I be tested for anything that may be causing my miscarriages since it's been a total of four now for me.
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  #5  
December 21st, 2013, 08:09 PM
plan4fate's Avatar I may bend, but not break
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Though no one, not even doctors can tell me why... almost every single one of my rpl friends has this.... they say that only the harder cases need treatment.. but all but ONE of the people I know has not had a successful pregnancy post diagnosis thanks to blood thinners and extra folic/folate.
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~TTC #1 together 2 years and counting ~


Awesome siggy made by Jaidynsmum

Me: Hashi's, PCOS, Insulin resistant, Multiple miscarriages
Polypectomy - 08/21/14 Laproscopy - 12/05/2014
Him: MFI low count, low morphology, low motillity
Seeing MFI specialist/RE in 2015. Vitamins started August 2nd
Cycle 1: Clomid cd3-7 ~ bfn
Cycle 2: Clomid cd 3-7 ~ beta negative (< 3)
Cycle 3: Lap on cd 2 - Femara cd 3-7 - Testing Christmas Day
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  #6  
December 22nd, 2013, 10:31 AM
butterfly721's Avatar TTC #1
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Oh, okay. I didn't know this was that common. I hope that you are able to get some answers soon.
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  #7  
December 26th, 2013, 08:37 AM
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I thought you were supposed to avoid ALL asprin if you were ttc or pregnant because of the Reyes risk? (based soley on what I've read on the back of asprin bottles)
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  #8  
December 26th, 2013, 12:52 PM
plan4fate's Avatar I may bend, but not break
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It becomes one of those things were the benefits out weigh the risks.

Reye's is more of a risk if you give the drug to children. I wouldn't use it nursing (and I could sob saying that because my AF's are SOOOO heavy and painful with out the aspirin) unless my OB and my own research showed that the risk is low.

About Reyes:
" The exact cause is unknown and, while it has been associated with aspirin consumption by children with viral illness, it also occurs in the absence of aspirin use."
A small, but disputed study also showed that the drug in Tylenol might also increase the risk.
__________________
~TTC #1 together 2 years and counting ~


Awesome siggy made by Jaidynsmum

Me: Hashi's, PCOS, Insulin resistant, Multiple miscarriages
Polypectomy - 08/21/14 Laproscopy - 12/05/2014
Him: MFI low count, low morphology, low motillity
Seeing MFI specialist/RE in 2015. Vitamins started August 2nd
Cycle 1: Clomid cd3-7 ~ bfn
Cycle 2: Clomid cd 3-7 ~ beta negative (< 3)
Cycle 3: Lap on cd 2 - Femara cd 3-7 - Testing Christmas Day
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