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I use Desitin in the purple box whenever Abby breaks out in a rash. She's only had 2 so far and they cleared up within a day, which is awesome because Aidan had a diaper rash too often for my liking when he was a baby.
The nicu was using A&D ointment on the rash Archer had in there. He had diahrea in there. They sent it home with us and I used it for a couple of days. No problem since so we haven't used anything. I was given destin on a diaper cake so I have that to try if needed.
Ive only had to use it one time overnight becuase she was pooping so much that it gave her a slight rash. We havent had any other issues, she is 100% CD so i think that has a lot to do with it, and we do change her diaper very often.
I never use a cream unless there's a rash. Kate only had a few but they were really bad (from really acidic poops during teething), I had to use a mix of different creams and oatmeal that time to clear it. Ember hasn't had any issues - but she does NOT like a wet or dirty diaper and will cry until I change it. I change a LOT of diapers every day!
Gianna is always somewhat red so I use cream at almost every change. The only cream that worked real well for my DS was Arbonne diaper cream and my friend sells it so I got a few tubes and have been using it on Gianna... Only thing that sucks is it is like $17 a tube!!!