I'm interested to see what others have to say. I have caught myself about to pour fabric softener in the diaper wash or put a bounce sheet in the dryer quite a few times

I'm sure I'll space out and do it eventually.... I would just try it and see what happens. If it were an entire load of diapers it might be worth stripping them to be on the safe side. For just one insert I would probably just use it at a time when I knew I'd be home in case it leaked and lo needed an outfit change.