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Their purpose is to move the yucky stuff out of the body, but if there is an infection they can swell up, sometimes being very tender. Right now I have a swollen one and it's super irritating. I'm applying witch hazel + tea tree oil on the skin so it can be absorbed that way, and also taking Acidophilus (probiotic pill).
Oh, and also taking garlic and cutting it in pill sized pieces and just swallowing it.