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Anything that is in a liquid state has the risk of being less effective based on whatever it is compounded with. Something like cough syrup is quite stable whereas something like antibiotics or an acid reduction agent is less stable.
Prilosec granules are in their optimum state as a granule. They are enteric coated so as not to be digested until they are passed through the stomach.
When you make it into a liquid, you don't have that luxury, so a lot of it can be affected by the stomach acid itself and only marginally effective in some people.
We found prilosec liquid was just a pure waste of time. I can imagine it's the same with any PPI that the pharmacy is compounding.
I would think anything that is putting hard pressure onto her back will cause an upset. There is a sort of negative pressure that is exerted onto the esophagus which can cause quite a bit of pain.
Can you look into a hammock or baby swing to keep her more upright? If you can elevate the pack n play, that might help as well.
Make sure to keep the dose accurate for the Zantac as she will need it constantly upped as she gains weight. If you want to wean her off it, make sure you do it slowly as suddenly stopping any of these drugs can worsen the reflux.
What sort of milk is she taking?
Also, what is the genetic disorder, if you don't mind me asking. I have TRAPS and reflux is one of the symptoms.
Jen + Matt
Parents to Sophie, the Wondergirl Asperger's Syndrome
GERD & Constipation
We had to roll up a comforter under Danny's crib mattress to keep him elevated. It didn't elevate him much but it was enough that he wasn't laying flat but little enough that he didn't just roll down to the bottom of the crib. When he was quite young we did liquid prevacid as well and it worked wonderfully. I don't know much about prilosec though. Prevacid was the only medication that finally helped Danny. He still threw up at least a dozen times every day but he stopped screaming in pain when he did. We finally found out that at that point he had an egg allergy that made him throw up that often. He had another ph probe done yesterday and we will get those results back tomorrow but based on the endoscopy alone it looks like either reflux or the beginning stages of EoE. He has mild gastritis and esophagitis and many many many ulcers from his duodenum down into his small intestine.