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My son is being referred to a pediatric rheumatologist for various symptoms and a postive ANA of 1:320. I have Raynauds and my sister and Grandpa both have positive ANA's as well (same pattern as my sons). My sister was released from rheum due to lack of symptoms and my Grandpa has Crohns. So I'm not sure if his ANA just means someday he MIGHT develop an autoimmune disease or if he already has one. His symptoms are vague - finger pain, headaches, swollen glands. Normal CBC. Normal sed rate and some other tests. He is also very small compared to my other kids.
Anyone have insight/advice or info on what to expect at Rheum appt?
I don't really have much I can tell you, except that my daughter had an inexplicable rash once (I think it was associated with a virus), and they did blood tests and her ANA came back positive (not sure by how much though). All the pediatrician said was that it meant there was an increased chance that she MIGHT develop something like rheumatoid arthritis someday. I didn't know anything about ANA back then, so I didn't really ask any more.
Now that I have an autoimmune disease, however, and I've read that that can lead to positive ANA's in children, I wonder if she'll end up with what I've got (Sjogren's and possibly CREST).
What pattern did your son have? Did they test for any specific antibodies? If not, they might do that; negative doesn't mean for sure that he doesn't have anything (I don't test positive for anything but ANA), but positive for specific antibodies would point them towards a diagnosis.
Sorry I can't be more help. Hope the appointment goes well.