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first off i am very sorry for your sisters loss. If she has a way to get on the internet i suggest she come over to ttc after a loss, there is a great group of ladies over there who are great at showing support!
second, she has very good chances of concieving on clomid. it stimulates your ovaries and helps to produce more eggs and mature eggs. With her history of twins and taking clomid she has a good chance of having another set. i wish her the best.
Sorry I replied so late, but are you sure that they don't have two different blood types? For instance I am Rh-negative and my husband has positive blood type. So I miscarried 3yrs ago cause my antibodies killed off the baby because it was a foreign body. Which they have an immune globulin shot for that, which should be give at the termination of the pregnancy and at 18wks of pregnancy. I heard clomid is good to take cause it stimulates your ovaries. I hope I was some help.
I don't know a lot about genetic things and blood types, but usually Clomid is given for problems with ovulation, concieving, or progesterone. Strickly from what you said, to me it seems like the conception wasn't the problem, it was something genetic that caused the problem. I am definately not a doctor, but if it was the blood types that caused the problem, then I don't think Clomid would be the answer. I would recommend seeing a genetic counselor or fertility specialist that deals with that sort of thing.
I agree, it doesn't sound like lack of ovulation was the issue. If you are ovulating well there is no reason to take clomid, it won't help the problem. I agree, was it maybe different kinds of blood? My dh and I have the same blood type, as I imagine lots of couples do and there was no issue. But if one of you has rh+ and one rh- there can be problems. I would suggest she go and see a specialist or at the very least her OB and talk to him/her and see what they can do.
I agree with the blood type, thank goodness, my Dh and I are both RH pos so I didnt need the shot. But my father and mother one is RH pos other is neg she needed the shot. I am sorry of her loss.
I would tell her to go back to the fertility specialist, it does sound like she could use clomid if she hasnt had an AF at all. Sounds like she isnt ovulating, best thing to do is go back to the dr and he will do tests to make sure she doesnt have endo or pcos then he will give her what she needs.