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Forum: Trying to Conceive after Loss


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February 19th, 2013, 02:49 PM
Just keep breathing.
Join Date: Sep 2012
Posts: 1,734
So, just a heads up to anyone who is interested in pre-pregnancy genetic testing- I have recently used 23andme.com for genetic testing on myself. I have had 2 pregnancy losses. I have an HMO. Before going all out with full testing and an RE and everything, my HMO's rule is that I have to have 3 losses. I don't want to wait for a third loss before doing what I can to find out the cause (or rule out potential problems). I'm not advertising for this company- I'm just a regular person, who wants to do everything in my power to protect my health and become a mom. 23andme is only one of several companies out there who do this, so feel free to do your research. I bought a kit online for $99, they sent me a test tube that I spit into, mailed it back, and within 3 weeks had results.

It can tell you if you have one of the two MTHFR gene variations that affect how your body processes folic acid. It can also tell you if you have Factor V Leiden, prothrombin or Factor 2 genetic blood clotting problems. It can also tell you if you are a carrier of the most common genes leading to cystic fibrosis.

There are still many issues that this doesn't test for, but for me it felt amazing to be able to rule some things out.

Unrelated to pregnancy, this testing gives you a LOT of health information. We learned that both my husband and I lack a gene that creates an enzyme that protects your lungs from damage. My husband used to be a smoker, so when we told his doctor about this, she ordered him a chest x-ray to check for damage and can do some things to help him. I also learned I have a higher genetic risk of Alzheimers, so I can do what I can (extra exercise, healthy eating, mental exercise, etc) to prevent that.

It's not for everybody- if you tend to get very anxious over potential health problems, it's not a great idea.

It's the best $99 I ever spent. When I told my OB what I did and how much (little) it cost, she was astounded- the HMO charges tons for these same tests.
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February 19th, 2013, 04:22 PM
Redneck_Mommy's Avatar Mega Super Mommy
Join Date: Sep 2012
Location: SE Texas
Posts: 1,503
Thanks for the info. Since my MTHFR diagnosis, my sister wants to get tested but doesn't have the money for that right now. I bet she could do the $99 though! I did some reading on that site, it does detect one variant of that particular mutation. There are more than one, but it's a start... Thanks again!
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