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New here Progesterone? (M/c) Please help

Forum: Trying to Conceive with Medical Assistance


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December 24th, 2010, 11:41 AM
Grace's Avatar Seven is Heaven
Join Date: Jun 2010
Posts: 3,506
Im not sure if this is the right place and if this is concidered medical assistance, but heres my story and my questions.
I had a tubal reversal in May im 28 dh is 30, I have children from a previous marriage, dh has none. We got pg very quickly without trying in July and I got my bfp at 11 dpo, the pg test got darker every day until 15 dpo when they got lighter and then finally a bfn, I m/ced at 5 weeks 2 days. We decided to not ttc for awhile and then in October we used opks and at night on 10 dpo I got what I thought was an indent line on Answer test, but the next day it was more clear bfp, but it took the digi another 2 days to pick it up, my hcg at 14 dpo was 24, prog was 13.01, I was put on prometrium but 2 days later my hcg dropped to 11 and then I m/ced again. My specialist is not concerned yet unless I have 3 m/c and since they are so early hes not worried but said he will do a uterin biopsy if I have a third loss. My OB says she thinks its a progesterone issue and she wants me to use opks and then take prometrium 2 days after + opk until cd 28 and if I got a bfp, I stay on prometrium if I get bfn then I stop the meds. So this cycle, we only bd once and it wasnt near O but I felt odd so just incase I took the premetrium, and although I did not get pg I notice that when I quit the meds to let af start my cycle is so much iddfferent, I usually clot a lot and have very heavy bleeding, ( i have to wear a pad and tampon), this cycle I had 1 clot, the bleeding was a little heavy on day 1 and very light on day 2 and then today, day 3 its spotting. So i guess its the progesterone that I took this cycle working and fixing something? I read online about signs of low progesterone and I have a lot of those signs, like heavy af, clots, water retention, fibrocystic breast and so on.

So heres me questions, has anyone here taken progesterone after ovulation and had a successfull pg? Has anyone taken the meds and noticed good changes with af?
My cycles have always been bad, but after my tubal ligation they got worse.
I seem to ovulate just fine, but my dr sometimes talks about clomid, is it possible shes talking about clomid to try to get better egg quality? Any thoughts or experiences on this would be helpful, we are ttcing again this cycle with opk and progesterone. We plan on having dh sperm checked soon, but at this point all Drs. thinks its my uterus. This last loss we had in October was not the same as the one in July, the lines on the test were so much lighter, like it was a weak pg from the start, but the one in July seemed very strong until 15 dpo. Thanks in advance.

7/2010 10/2010 05/2012

Last edited by Grace; December 24th, 2010 at 12:59 PM.
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December 26th, 2010, 07:04 AM
Platinum Supermommy
Join Date: Oct 2004
Location: *queen city* of North Carolina
Posts: 9,497
I'm in the same boat wondering if it will work with progestrone. I'm tired of getting poked and proaded every other week or every week it seems like!
Have you talked to you OB about doing any testing to see where your progestrone is and such on a typical cycle?
We did a bunch of blood work as a first step to rule out any genetic translocation or clotting issues. I too, have never had problems getting pregnant. However, 3/4 of my pregnancies have ended in m/c. And the mystery of how I stayed pregnant with my daughter baffles everyone considering how my cycle is and how low my progestrone level is.
After we did the blood work, and everything was fine. The OB suggested a 3-part evaluation for FSH, progestrone, and ultrasound (CD 3, CD 21, and CD 14). I've gotten everything but CD 3 done (I missed that one, but will on my next cycle). However, just from CD 14 and CD 21, it was very eye opening and confirmed our suspisions. From what the OB told me, she knew it was likely a progestrone issue but doing this "evaluation" helps to determine how deficent I am and when I am O'ing, and just overall understanding my cycle. I guess, it determines what type of progestrone they give you and how much, and when in your cycle and for how long.
In my case, the OB wants me to do an injection of progestrone on CD 21 followed by suppositories *sp* until AF or 10-12 weeks pregnant. My OB did suggest doing clomid and a trigger shot, because on CD 14 I had a mature follicule however I don't think I O'ed until CD 17-18 at the earliest (I don't temp or use OPK but am going to start - I didn't have any CM period until CD 17-18). Her logic is, doing clomid will ensure that my egg quality is good and the trigger shot will help me O at the right time and therefore help determine when I need to do the progestrone. The OB said we didn't have to do the clomid or trigger shot, but thinks it will help with timing and teaching my body what to do and when (my normal cycle is at least 35 days)!
I have no idea if we'll get pregnant and stay pregnant (which staying pregnant seems to be our problem). We'll start doing all of this next cycle. I'm crossing my fingers that this is all we have to do. (And I so didn't mean for this to be a book...)
Proud Mommy To My Princess (5)
Watching over us -- August 2005, March 2010, October 2010, July 2011
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