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Progesterone Levels During Pregnancy

What is progesterone?

Progesterone is a hormone produced by the ovaries that helps prepare the uterus for pregnancy. It is first produced by the corpus luteum in the ovaries and later is maintained by the placenta.

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What does progesterone do?

  • Helps to regulate the menstrual cycle.
  • Prepares the lining of the uterus for implantation.
  • Keeps the lining of the uterus thick which is necessary for a successful pregnancy.
  • Produces a rise in temperature after ovulation, which remains until menstruation occurs.
  • Creates a nutrient rich environment for the baby by increasing glycogen and arterial blood to the lining of the uterus.
  • Keeps the uterus from having contractions.
  • Causes the cervix to thicken and create a mucous plug which prevents bacteria from entering the uterus.

What are normal progesterone levels?

Progesterone during menstrual cycle

Day 1-14 

 >1 to 1.5 ng/ml

Day 15-28

2-28 ng/ml

Progesterone during pregnancy

First Trimester 9-47 ng/ml
Second Trimester  17-147 ng/ml
Third Trimester 55-200 ng/ml

Sometimes doctors will check a woman's progesterone level during pregnancy.  Most doctors like to see a minimum level of 10 ng/ml during the first few weeks of pregnancy.   If a woman has low progesterone levels this can be an indication of a threatened miscarriage.  If you are concerned about your progesterone level talk to your doctor for more information.


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