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Progesterone Levels During Pregnancy

What is progesterone?

Progesterone is a hormone produced by the ovaries that helps prepare the uterus for pregnancy. It is first produced by the corpus luteum in the ovaries and later is maintained by the placenta

What does progesterone do?

  • Helps to regulate the menstrual cycle.
  • Prepares the lining of the uterus for implantation.
  • Keeps the lining of the uterus thick which is necessary for a successful pregnancy.
  • Produces a rise in temperature after ovulation, which remains until menstruation occurs.
  • Creates a nutrient rich environment for the baby by increasing glycogen and arterial blood to the lining of the uterus.
  • Keeps the uterus from having contractions.
  • Causes the cervix to thicken and create a mucous plug which prevents bacteria from entering the uterus.

What are normal progesterone levels?

Progesterone during menstrual cycle
Day 1-14   >1 to 1.5ng/ml
Day 15-28 2-28 ng/ml
Progesterone during pregnancy
First Trimester 9-47
Second Trimester  17-147 ng/ml
Third Trimester 55-200 ng/ml

Sometimes doctors will check a woman's progesterone level during pregnancy.  Most doctors like to see a minimum level of 10 ng/ml during the first few weeks of pregnancy.   If a woman has low progesterone levels this can be an indication of a threatened miscarriage.  If you are concerned about your progesterone level talk to your doctor for more information.

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